Lo Dico Alessia
Bio sketch
Master degree in Biology
PhD in Molecular and Translational Schoo
ORCID ID: 0000-0002-8627-5050
Scopus Author ID: 55838594500
Research field
New strategies for overcoming chemoresistance
Characterization and analysis of microRNAs
Molecular imaging applied at oncological models
In vitro and in vivo identification of biomarkers
National collaboration
Università degli Studi di Milano, Dipartimento di Fisiopatologia medico-chirurgica e dei trapianti
Università degli Studi di Milano- Bicocca, Dipartimento di Medicina e Chirurgia, Monza
Ospedale San Raffaele, Unità di Medicina Nucleare, Milano
Università degli Studi di Palermo, Dipartimento di Biopatologia e Biotecnologie mediche
Recent Bibliography
Valtorta S, Lo Dico A, Raccagni I, Martelli C, Pieri V, Rainone P, Todde S, Zinnhardt B, De Bernardi E, Coliva A, Politi LS, VielT, Jacobs AH, Galli R, Ottobrini L, Vaira V, Moresco RM. “Imaging Metformin Efficacy as Add-On Therapy in Cells and Mouse Models of Human EGFR Glioblastoma” Front Oncol 2021; 11: 664149 doi: 10.3389/fonc.2021.664149
Lo Dico A*, Martelli C, Diceglie C, Ottobrini L (*First author)“The Multifaceted Role of CMA in Glioma: Enemy or Ally?” Int J Mol Sci. 2021 Feb 23;22(4):2217. doi: 10.3390/ijms22042217
Cava C, Novello C, Martelli C, Lo Dico A, Ottobrini L, Piccotti F, Truffi M, Corsi F, Bertoli G, Castiglioni I. “Theranostic application of miR-429 in HER2+ breast cancer” Theranostics 10(1):50-61. doi: 10.7150/thno.36274
Lo Dico A*, Salvatore D, Martelli C, Ronchi D, Diceglie C, Lucignani G, Ottobrini L L (*First author)“Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma” Cells 8(11):1315. doi: 10.3390/cells8111315.
Lo Dico A*, Valtorta S, Ottobrini L, Moresco RM (*First author).“Role of Metformin and AKT Axis Modulation in the Reversion of Hypoxia Induced TMZ-Resistance in Glioma Cells”. Front Oncol 2019; 9: 463
Lo Dico A*, Martelli C, Diceglie C, Lucignani G and Ottobrini L (*First author). “HIF-1a activity as a switch for GBM responsiveness to TMZ” Front Oncol 2018 Jun; 8: 249
Valtorta S, Lo Dico A*, Raccagni I, Gaglio D, Belloli S, Politi LS, Martelli C, Diceglie C, Bonanomi M, Ercoli G, Vaira V, Ottobrini L, Moresco RM (*First author). “Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models” Oncotarget 2017 12; 8: 113090-113104
Lo Dico A* Costa V, Martelli C, Diceglie C, Rajata F, Rizzo A, Mancone C, Tripodi M, Ottobrini L, Alessandro R, Conigliaro A (*First author). “MiR675-5p Acts on HIF-1α to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma” Theranostics 2016; 6: 1105-18.
Conigliaro A, Costa V, Lo Dico A*, Saieva L, Buccheri S, Dieli F, Manno M, Raccosta S, Mancone C, Tripodi M, De Leo G, Alessandro R (*First author). “CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA” Mol Cancer 2015 Aug; 14: 155
Lo Dico A*, Martelli C, Valtorta S, Raccagni I, Diceglie C, Belloli S, Gianelli U, Vaira V, Politi LS, Bosari S, Lucignani G, Moresco RM, Ottobrini L (*First author). “Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model” Eur J Nucl Med Mol Imaging 2015 Jun; 42: 1093-105